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Matsue is located in southwest Japan, in the north of Shimane Prefecture
. Shimane is part of the Chugoku Region
, along with four other prefectures (Tottori, Okayama, Hiroshima, and Yamaguchi).
The Chugoku Region is commonly subdivided into the San-yo Region (south side) along the Seto Inland Sea coast, and the San-in Region
(north side) along the Sea of Japan coast, of which Matsue is the largest city.